Comorbidities and associated diseases in psoriatic disease

Abstract:

Today, psoriasis is considered an inflammatory multisystemic disease that can affect the skin and many other organ systems in the form of comorbidities such as hypertension, diabetes, cardiovascular disease, inflammatory bowel and eye diseases, and psychosocial comorbidities. Psoriasis patients are twice as likely to develop obesity, hypertension and cardiovascular insufficiency, and 1.5 times more likely to develop diabetes and myocardial infarction. Patients with severe psoriasis have an increased cardiovascular mortality due to the development of hypertension, heart failure, and coronary artery disease. Therefore, according to clinical guidelines, the dermatologist should inform the patient about psoriasis and the possible increased risk for the development of comorbidities, especially metabolic diseases. The approach to the patient with psoriasis must be comprehensive and multidisciplinary, including the treatment of psoriatic disease with prevention, early identification and appropriate treatment of comorbidities.

Key words:
associated diseases; cardiovascular disease; comorbidities; metabolic syndrome; psoriasis