MEDIX, God. 14 Br. 75/76  •  Pregledni članak  •  Interna medicina HR ENG

Intenzivno liječenje statinima u akutnom koronarnom sindromuThe intensive statin therapy in patients with acute coronary syndrome

Mario Ivanuša

Na početku XXI. stoljeća više nije sporno da statine trebe rabiti kao dio modernog farmakoinvazivnog liječenja akutnog koronarnog sindroma (ACS). Studije MIRACL, PROVE-IT i Phase Z of the A to Z utvrdile su da visoke doze statina u ranoj fazi ACS (tzv. intenzivno liječenje statinima) djelotvorno smanjuju učestalost velikih neželjenih srčanožilnih događaja. Ovo liječenje u bolesnika s ACS je sigurno i isplativo. Daljnja istraživanja definirat će optimalnu duljinu intenzivnog liječenja statinima

Ključne riječi:
akutni koronarni sindrom, akutni infarkt miokarda, statini

Članak u cijelosti pročitajte u tiskanom izdanju MEDIX, God. 14 Br. 75/76

At the beginning of the 21st century there is no furhter doubt that statins are to be used as modern pharmacoinvasive treatment of acute coronary syndrome (ACS). The studies MIRACL, PROVE-IT and Phase Z of the A to Z have established that high-statin doses in an early ACS stage (so called intensive statin therapy) efficiently reduce the frequency of undesired cardiovascular events. This treatment of patients with ACS is safe and cost-effective. Further research will define an optimal length of the intensive statin therapy.

Key words:
acute coronary syndrome, acute myocardial infarction, statins