Diagnosis of multiple sclerosis

Abstract:

In diagnosis of multiple sclerosis (MS), anamnesis and neurological status have an irreplaceable role since the signs and symptoms may resemble those of other diseases. Clinically, it is necessary to determine the value of EDSS (Expanded Disability Status Scale) which provides an objective quantification of disability in patients with MS. The most important para-clinical criterion for the diagnosis of MS is magnetic resonance imaging (MRI). Together, with the new diagnostic criteria, one can diagnose the disease on the basis of just a single MRI. Although, evoked potentials and cerebrospinal fluid findings are no longer part of the diagnostic criteria for relapsing-remitting form of MS (RRMS), their use and interpretation as part of the clinical and MRI findings may contribute to the correct diagnosis in diagnostically doubtful cases. 

Key words:
cerebrospinal fluid; EDSS; evoked potentials; MR