Psychiatric disorders in patients with multiple sclerosis

Abstract:

Neuropsychiatric manifestations represent an important aspect within multiple sclerosis since patients have a higher incidence of mental disorders compared to the general population. The most common psychiatric disorders in multiple sclerosis are depression, anxiety disorders (generalized anxiety disorder, panic disorder and obsessive compulsive disorder), bipolar disorder, psychotic disorders, personality disorders, alcohol abuse or addiction, drug abuse or addiction, and pseudobulbar affect. The high prevalence of psychiatric comorbidities in multiple sclerosis patients is further associated with various negative consequences such as reduced quality of life and functional status, non-adherence to therapy, negative impact on disease progression, and increased suicidal risk. Early diagnosis and treatment of these disorders is vital for both sufferers and their caregivers.

Key words:
comorbidity; multiple sclerosis; psychiatric disorders; quality of life