Use of octenidine dihydrochloride in eradication of MRSA carriage

Abstract:

Due to its chemical structure and high antimicrobial efficacy, octenidine dihydrochloride may be considered a universal antimicrobial agent that exerts its activity against Gram-positive and Gram-negative bacteria and fungi. Octenidine dihydrochloride is primarily used in antiseptic skin care and eradication of methicillin-resistant Staphylococcus aureus (MRSA ) carriage on the skin and scalp, antiseptic care of wounds and burns and care of mucous membranes. MRSA causes infections of the skin and subcutaneous tissue, respiratory tract and central nervous system and sepsis. Therefore, eradication of MRSA carriage in hospital setting is highly important. Eradication of MRSA carriage is performed according to eradication principles, in cycles following schedule of eradication by using octenidine dihydrochloride. Success of MRSA eradication is evaluated by analysis of the swabs taken from different body sites. 

Key words:
anti-infective agents, local; methicillin resistant Staphylococcus aureus; octenidine