MEDIX, God. 26 Br. 143  •  Pregledni članak  •  Dermatovenerologija HR ENG

Što je to psorijatična bolest?What is psoriatic disease?

Iva Dediol, Nika Franceschi, Mirna Šitum

Psorijatična bolest je kronična sustavna upalna bolest koja primarno zahvaća kožu i zglobove uz druge organske sustave. Bolest se može pojaviti u bilo kojoj životnoj dobi te predstavlja velik psihosocijalni teret za bolesnike. U psorijatičnoj je bolesti prisutna u cijelome organizmu kronična blaga sustavna upala, što se odražava komorbiditetima, uključujući psorijatični artritis, kardiovaskularne bolesti, depresiju i anksioznost, nealkoholnu bolest jetre, debljinu i pridružene bolesti poput upalne bolesti crijeva. Psorijatični plak obilježen je eritemom i ljuskama s najčešćom lokalizacijom u vlasištu, ekstenzornim stranama udova uz zahvaćanje noktiju, ali može zahvatiti i čitavu površinu kože. Bolesnici se žale na fizičke simptome poput svrbeža, zatezanja kože i bola, što im dodatno remeti svakodnevni rad i aktivnosti. Standardizirani instrumenti PASI (engl. Psoriasis Area Severity Index), BSA (engl. Body Surface Area) i DLQI (engl. Dermatology Life Quality Index) primjenjuju se za određivanje težine bolesti i utjecaja na kvalitetu života, što kliničaru određuje izbor liječenja.

Ključne riječi:
etiologija; klinička slika; PASI; psorijatična bolest

Članak u cijelosti pročitajte u tiskanom izdanju MEDIX, God. 26 Br. 143

Psoriatic disease is a chronic systemic immunologic disease that primarily affects the skin and joints, along with other organ systems. It can occur at any age and represents a high psychosocial burden on patients. A chronic mild systemic inflammation is present throughout the body and manifested through comorbidities, such as psoriatic arthritis, cardiovascular diseases, depression and anxiety, non-alcoholic fatty liver disease, obesity, as well as associated diseases such as inflammatory bowel disease. A psoriatic plaque is characterized by erythema and scales, and is most commonly found on the scalp, extensor sides of the extremities and nails, but can also affect the entire surface of the skin. Patients suffer from itching, tightness of skin and pain which further disrupts their daily work and activities. PASI (Psoriasis Area Severity Index), BSA (Body Surface Area) and DLQI (Dermatology Life Quality Index) are standardized tools used to determine the severity of the disease and impact on quality of life, determining the clinician’s choice of treatment.

Key words:
clinical picture; etiology; PASI; psoriasis