MEDIX, God. 17 Br. 96  •  Pregledni članak  •  Infektologija HR ENG

Bolesti povezane s humanim papiloma virusomHuman papillomavirus-related diseases

Suzana Ljubojević, Mihael Skerlev

Infekcija humanim papiloma virusom (HPV) smatra se najčešćom virusnom spolno prenosivom bolešću. Do danas je poznato više od 100 različitih vrsta HPV-a koji su povezani s različitim kliničkim slikama promjena kože i sluznice: od benignih bradavica, šiljastih kondiloma, do preinvazivnih i invazivnih promjena cerviksa, vulve, vagine, penisa i anusa. Bolesti povezane s HPV-om mogu se podijeliti na kožne i sluznične lezije genitalnog i ekstragenitalnog područja. Ostale promjene kod kojih se može izolirati HPV su: melanom, nemelanomski kožni karcinomi, aktiničke i seborejičke keratoze, epidermalne ciste, ekstragenitalna Bowenova bolest, Pagetova bolest, invazivni karcinom dojke, lichen sclerosus, psorijatički plak, pa čak i zdrava koža prethodno ozračena umjetnim UV-zrakama. 

Ključne riječi:
genitalne bolesti u muškaraca; genitalne bolesti u žena; novotvorine kože; papiloma virusi; šiljasti kondilomi

Članak u cijelosti pročitajte u tiskanom izdanju MEDIX, God. 17 Br. 96

Genital human papillomavirus (HPV) infections are among the most common sexually transmitted diseases. Over 100 distinct HPVs have been identified and each is associated with a specific set of clinical lesions. They cause a wide spectrum of diseases, from benign verrucae vulgares and condylomata acuminata to the malignancies of the cervix, vulva, vagina, penis and anus. Diseases associated with HPV infection can be divided to skin and mucosal lesion of genital and extragenital region. Other HPV-associated diseases include melanoma, non-melanoma skin cancer, actinic and seborrhoeic keratosis, epidermal cyst, extragenital Bowen’s disease, Paget’s disease, invasive breast cancer, and lichen sclerosus psoriatic plaque. Cutaneous HPV can even be found on healthy skin previously exposed to artificial UV radiation. 

Key words:
condylomata acuminata; genital diseases, female; genital diseases, male; papillomaviridae; skin neoplasms