MEDIX, God. 14 Br. 77  •  Pregledni članak  •  Pedijatrija HR ENG

Autistički spektar poremećajaAutistic spectrum disorder

Goran Krakar, Vlatka Mejaški Bošnjak

Od uvođenja pojma autizam i prvog kliničkog opisa do uvođenja pojma autističkog spektra poremećaja proveden je velik broj studija o pervazivnim razvojnim poremećajima. Autistički spektar poremećaja predstavlja složen neurorazvojni poremećaj, a ne jedinstvenu bolest. Dijagnoza se postavlja na temelju multidisciplinarnog pristupa, a u sebi objedinjuje duže promatranje ponašanja, ciljane i prilagođene upitnike, neuropedijatrijsku obradu, psihijatrijski pregled, metaboličku, toksikološku, gastroenterološku te genetsku obradu. Uzevši u obzir pridružene sindrome, njihove uzroke i objašnjenja sigurno je da se radi o multikauzalnoj etiologiji pri čemu različiti uzroci rezultiraju stanjima slične kliničke slike, koja se javljaju u ranom djetinjstvu, a traju cijeli život

Ključne riječi:
autistički poremećaj; autistički poremećaj, dijagnoza; autistički poremećaj, epidemiologija; pervazivni razvojni poremećaji u djece

Članak u cijelosti pročitajte u tiskanom izdanju MEDIX, God. 14 Br. 77

Since the term autism was first introduced and clinically described, a significant number of studies in pervasive developmental disorders have been performed. Gradually, the term autism was replaced by the term autistic spectrum disorder. This article brings recent knowledge about epidemiology, etiology, clinical aspects, associated syndromes, and possibilities of early diagnosis and intervention in patients with autistic spectrum disorder. Since autistic spectrum disorder is not a single entity, but rather a complex neurodevelopmental disorder, it is diagnosed on the basis of multidisciplinary approach that combines longer behavioural observation, specific questionnaires, clinical neuropaediatric diagnosis, psychiatric evaluation, and metabolic, toxicological, gastroenterological and genetic diagnostic work up. Concerning all associated syndromes and their causes, it is certain that the etiology of autistic spectrum disorder is multicausal and that different causes may result in a similar clinical picture, which appears in early childhood and lasts for a lifetime

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